recQ [2018-12-07 16:50:36]

ATP-dependent DNA helicase, acts together with RecJ

Locus: BSU19220

Isoelectric point: 5.92

Molecular weight: 67.18 kDa

Protein length: 591 aa

Gene length: 1773 bp

Function: control of DNA recombination, maintenance of genomic stability

Product: ATP-dependent DNA helicase

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Information processing → Genetics → DNA replication
• Information processing → Genetics → DNA repair/ recombination → Other proteins
• Information processing → Genetics → DNA repair/ recombination/ based on similarity

Gene

Coordinates: 2,094,010 → 2,095,785

The protein

Catalyzed reaction/ biological activity

• unwinds covalently closed ds DNA (in complex with SSB) PubMed
• RecQ controls Topo III (de)catenation activity PubMed

Paralogous protein(s)

• RecS

Structure

• 4O3M (Bloom's syndrome helicase, 35% identity) PubMed

Expression and Regulation

Operons

• Genes: bsrB-recQ-yocH
  Description: PubMed

Biological materials

Mutant

• MGNA-B414 (yocI::erm), available at the NBRP B. subtilis, Japan
• BKE19220 (ΔrecQ::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATAACGTGTAAACCTCGCT, downstream forward: _UP4_TAAAAAAACAGAAAAACAAT
• BKK19220 (ΔrecQ::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATAACGTGTAAACCTCGCT, downstream forward: _UP4_TAAAAAAACAGAAAAACAAT

References

Reviews

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Original publications

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